The recent finding of the microbiota–gut–brain axis indicates the bidirectional connection between our gut and brain, demonstrating that gut microbiota can influence many neurological disorders such as autism. Recent studies on the gut–brain axis suggested that the gut contains millions of nerve cells, eventually forming an extensive network called the enteric nervous system (ENS). This enteric nervous system is also considered our second brain. Neurotransmitters produced in the gut influence our emotions by regulating the gut–brain axis. Around 90% of neurotransmitters, such as serotonin, are produced in the gut. The average human gut contains 1 kg of diverse groups of bacteria that mostly perform beneficial activities often involved in metabolites production and transportation and maintenance of gut homeostasis. Progurt’s human probiotic isolates withstand stomach acids, which destroy most probiotics, to enter and be absorbed by the human gastrointestinal tract. Progurt creates gut homeostasis and strengthens the gut microbial lining. Progurt’s human strain microbiota positively affects our emotions and neurological disorders via the gut-brain axis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355470/